|
KMID : 0357920020360010045
|
|
Korean Journal of Pathology
2002 Volume.36 No. 1 p.45 ~ p.50
|
|
|
Posttransplant Lymphoproliferative Disorder: A Report of 4 Cases
|
|
Chang Sun-Hee
Huh Joo-Ryung
Kim Kyung-Mo
Han Duck-Jong
Lee Sung-Gyu
Yu Eun-Sil
|
|
|
Abstract
|
|
|
|
Posttransplant lymphoproliferative disorder (PTLD) is a proliferation of B-cells associated with Epstein-Barr virr virus (EBV) infection as a complication of immunosuppression, especially by FK506. We investigated four cases of PTLD which developed either in allografts or in other organs. Case 1 was a 38-year-old woman, who developed monomorphic PTLD in a kidney 7 years and 7 months after renal transplantation. Case 2 was a 37-year-old man, who developed monomorphic PTLD in the right submandibular lymph node 4 months after liver tarnsplantation. Case 3 was a 60-year-old man, who developed monomorphic PTLD in the liver 8 months after liver transplantation. Case 4 was a 2-year-old female chile, who developed polymorphic PTLD in the colon, liver, and mesenteric lymph node 10 months after liver transplantation. FK506 was administered to case 4. EBV was identified in the tissues of all cases by immunohistochemistry and/or in situ hybridization.
|
|
|
KEYWORD
|
|
|
Lymphoproliferative Disorders, Liver Transplantation, Kidney Transplantation
|
|
|
FullTexts / Linksout information
|
|
 
|
|
|
Listed journal information
|
|
  
|